American Plasma Users Coalition


APLUS is a coalition of national patient organizations created to address the unique needs of patients with rare diseases who use lifesaving plasma protein therapies. The organizations representing these patients share a common desire to ensure that the patient voice is heard when relevant public policies, regulations, directives, guidelines, and recommendations affecting access to safe and effective therapy and treatment are considered. Together, our coalition represents more than 125,000 Americans living with chronic disorders dependent upon plasma protein therapies for their daily living. Safety is of utmost concern to APLUS: we believe that plasma collection regulations should always prioritize the safety of the donor and the safety of the eventual plasma user. 

APLUS is proud to honor plasma donors as heroes. On behalf of the many people living with rare complicated diseases, APLUS thanks all plasma donors for their dedication to helping others. Without medicines created from source plasma, many patients represented by APLUS member organizations would not have the lives they are currently living now. To learn more about the plasma-using community, visit each member organization’s website to learn about each community and their work to help patients live their best lives while using plasma-derived medicines.

APLUS Member Organizations:

Alpha-1 Foundation -

Coalition for Hemophilia B -

Committee of Ten Thousand -

GBS|CIDP Foundation International –

Hemophilia Federation of America –

Immune Deficiency Foundation

Jeffrey Modell Foundation -

National Hemophilia Foundation -

Platelet Disorder Support Association

 US Hereditary Angioedema Association –

World Federation of Hemophilia -

News & Updates

Get the latest information on plasma through our news and updates. Featuring: Scientific discoveries, plasma supply, industry-related coverage, policy and legislation, and more!

Congressional Plasma Caucus formed to address concerns of constituents


Members of the congressional Plasma Caucus provide a venue to educate legislators on important legislation to provide access to patients who rely on immunoglobulin (Ig) therapy.
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Plasma demand is on the rise because of new patients and products


The need for plasma is forecasted to increase since more patients are being diagnosed with current and newly discovered rare conditions as well as additional indications being approved for plasma medications.
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Busting common plasma donation myths


Misconceptions about plasma donation, such as that it is bad for your health, lead to undue misapprehensions.
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How donated plasma treats trauma and shock


Studies show that giving patients plasma immediately after a traumatic injury improves survival rates significantly.
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Understanding the plasma ecosystem from donor to patient


Find out how plasma is collected, what happens after it’s collected, and who ultimately benefits from plasma-derived medicinal products (PDMPs).
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How plasma saved lives through the ages, from 1918 to WWII to today


Both convalescent plasma and plasma-based therapies have been around for some time, though many people are still unfamiliar with their history.
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