American Plasma Users Coalition


APLUS is a coalition of national patient organizations created to address the unique needs of patients with rare diseases who use lifesaving plasma protein therapies. The organizations representing these patients share a common desire to ensure that the patient voice is heard when relevant public policies, regulations, directives, guidelines, and recommendations affecting access to safe and effective therapy and treatment are considered. Together, our coalition represents more than 125,000 Americans living with chronic disorders dependent upon plasma protein therapies for their daily living. Safety is of utmost concern to APLUS: we believe that plasma collection regulations should always prioritize the safety of the donor and the safety of the eventual plasma user. 

APLUS is proud to honor plasma donors as heroes. On behalf of the many people living with rare complicated diseases, APLUS thanks all plasma donors for their dedication to helping others. Without medicines created from source plasma, many patients represented by APLUS member organizations would not have the lives they are currently living now. To learn more about the plasma-using community, visit each member organization’s website to learn about each community and their work to help patients live their best lives while using plasma-derived medicines.

APLUS Member Organizations:

Alpha-1 Foundation -

Coalition for Hemophilia B -

Committee of Ten Thousand -

GBS|CIDP Foundation International –

Hemophilia Federation of America –

Immune Deficiency Foundation

Jeffrey Modell Foundation -

National Hemophilia Foundation -

Platelet Disorder Support Association

 US Hereditary Angioedema Association –

World Federation of Hemophilia -

News & Updates

Get the latest information on plasma through our news and updates. Featuring: Scientific discoveries, plasma supply, industry-related coverage, policy and legislation, and more!

How plasma saved lives through the ages, from 1918 to WWII to today


Both convalescent plasma and plasma-based therapies have been around for some time, though many people are still unfamiliar with their history.
Read More

Science-based policies boost plasma donation globally


Science is driving global advancements in policy and allowing more people around the world to donate plasma while ensuring the safety of donors and the plasma collected.
Read More

How plasma-based therapies treat hemophilia


Plasma has been used to treat bleeding disorders like hemophilia since the 1950s, and is still one of the most effective treatment options for patients.
Read More

GBS, CIDP, and plasma


Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) are rare neurological disorders and plasma-based therapies are used to treat them.
Read More

FDA proposes risk-based rules for plasma and blood donations


On January 27, 2023, the U.S. Food and Drug Administration announced a draft proposal for eligibility rules for blood and blood product donation using “gender-inclusive, individual risk-based questions to reduce the risk of transfusion-transmitted HIV.”
Read More

Stiff person syndrome and plasma


SPS is a rare and progressive neurological disease. It affects one person in a million and Celine Dion is one of those people relying on plasma donation to treat the condition.
Read More
Powered By:
Mojo Creative Digital